Current status of reduced intensity conditioning allogeneic stem cell transplantation for acute myeloid leukemia
نویسندگان
چکیده
منابع مشابه
Current status of reduced-intensity-conditioning allogeneic stem cell transplantation for acute myeloid leukemia.
Allogeneic stem cell transplantation (allo-SCT) is the most efficient antileukemic treatment for acute myeloblastic leukemia (AML). However, elderly patients can rarely benefit from standard myeloablative allo-SCT because of an unacceptable rate of procedure-related toxicities. This point is critical when considering AML patients in first complete remission. The development of the so-called red...
متن کاملreduced intensity versus full myeloablative conditioning in allogeneic stem cell transplantation for acute myeloid leukemia
introduction: allogeneic hematopoietic stem cell transplantation (hsct) has been reported to be a successful curative treatment in aml patients. myeloablative conditioning (mac) is used more frequent as a preparing regimen. this study attempts to compare the outcome of patients who has received mac and reduced- intensity conditioning (ric). methods: totally, 618 patients with aml underwent hsct...
متن کاملReduced-intensity conditioning allogeneic hematopoietic cell transplantation in adults with acute myeloid leukemia.
BACKGROUND Acute myeloid leukemia (AML), whether de novo or arising from antecedent hematologic disorders in elderly patients, is less likely to be curable with standard chemotherapy regimens used for younger patients. Allogeneic hematopoietic cell transplantation (allo-HCT) is currently the most efficient anti-leukemia treatment for AML and has shown a survival advantage in younger patients wi...
متن کاملAllogeneic hematopoietic stem cell transplantation for relapsed acute myeloid leukemia in ETO positive with reduced-intensity conditioning
Objective This research is conducted under the intention of exploring the efficacy and safety of reduced-intensity conditioning for allogeneic hematopoietic stem cell transplantation (allo-HSCT) in the treatment of relapsed ETO positive acute myeloid leukemia (AML). Materials and Methods Treatment of 15 cases referring to recurrent ETO positive acute myeloid leukemia in an army hospital from ...
متن کاملReduced-intensity conditioning allogeneic stem cell transplantation in malignant lymphoma: current status
Allogeneic stem cell transplantation (allo-SCT) is a potential cure for patients with malignant lymphoma that is based on the graft-versus-lymphoma (GVL) effect. Myeloablative conditioning allo-SCT is associated with high mortality and morbidity, particularly in patients older than 45 years, heavily pretreated patients (prior hematopoietic stem cell transplantation or more than two lines of con...
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ژورنال
عنوان ژورنال: Haematologica
سال: 2007
ISSN: 0390-6078,1592-8721
DOI: 10.3324/haematol.10867